IL2 Receptor gamma (IL2RG) (NM_000206) Human Tagged ORF Clone Lentiviral Particle
SKU
RC204898L3V
Lenti ORF particles, IL2RG (Myc-DDK tagged) - Human interleukin 2 receptor, gamma (IL2RG), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | IL2 Receptor gamma |
Synonyms | CD132; CIDX; IL-2RG; IMD4; P64; SCIDX; SCIDX1 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC204898).
|
ACCN | NM_000206 |
ORF Size | 1107 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_000206.1 |
RefSeq Size | 1560 bp |
RefSeq ORF | 1110 bp |
Locus ID | 3561 |
UniProt ID | P31785 |
Cytogenetics | Xq13.1 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction, Endocytosis, Jak-STAT signaling pathway, Primary immunodeficiency |
MW | 42.3 kDa |
Summary | The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder. [provided by RefSeq, Mar 2010] |
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