IL2 Receptor gamma (IL2RG) (NM_000206) Human Untagged Clone

SKU SC127538

IL2RG (untagged)-Human interleukin 2 receptor, gamma (IL2RG)

Product Data

• Type: Human Untagged Clone
• Target Symbol: IL2 Receptor gamma
• Synonyms: CD132; CIDX; IL-2RG; IMD4; P64; SCIDX; SCIDX1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC127538 sequence for NM_000206 edited (data generated by NextGen Sequencing); ATGTTGAAGCCATCATTACCATTCACATCCCTCTTATTCCTGCAGCTGCCCCTGCTGGGA; GTGGGGCTGAACACGACAATTCTGACGCCCAATGGGAATGAAGACACCACAGCTGATTTC; TTCCTGACCACTATGCCCACTGACTCCCTCAGTGTTTCCACTCTGCCCCTCCCAGAGGTT; CAGTGTTTTGTGTTCAATGTCGAGTACATGAATTGCACTTGGAACAGCAGCTCTGAGCCC; CAGCCTACCAACCTCACTCTGCATTATTGGTACAAGAACTCGGATAATGATAAAGTCCAG; AAGTGCAGCCACTATCTATTCTCTGAAGAAATCACTTCTGGCTGTCAGTTGCAAAAAAAG; GAGATCCACCTCTACCAAACATTTGTTGTTCAGCTCCAGGACCCACGGGAACCCAGGAGA; CAGGCCACACAGATGCTAAAACTGCAGAATCTGGTGATCCCCTGGGCTCCAGAGAACCTA; ACACTTCACAAACTGAGTGAATCCCAGCTAGAACTGAACTGGAACAACAGATTCTTGAAC; CACTGTTTGGAGCACTTGGTGCAGTACCGGACTGACTGGGACCACAGCTGGACTGAACAA; TCAGTGGATTATAGACATAAGTTCTCCTTGCCTAGTGTGGATGGGCAGAAACGCTACACG; TTTCGTGTTCGGAGCCGCTTTAACCCACTCTGTGGAAGTGCTCAGCATTGGAGTGAATGG; AGCCACCCAATCCACTGGGGGAGCAATACTTCAAAAGAGAATCCTTTCCTGTTTGCATTG; GAAGCCGTGGTTATCTCTGTTGGCTCCATGGGATTGATTATCAGCCTTCTCTGTGTGTAT; TTCTGGCTGGAACGGACGATGCCCCGAATTCCCACCCTGAAGAACCTAGAGGATCTTGTT; ACTGAATACCACGGGAACTTTTCGGCCTGGAGTGGTGTGTCTAAGGGACTGGCTGAGAGT; CTGCAGCCAGACTACAGTGAACGACTCTGCCTCGTCAGTGAGATTCCCCCAAAAGGAGGG; GCCCTTGGGGAGGGGCCTGGGGCCTCCCCATGCAACCAGCATAGCCCCTACTGGGCCCCC; CCATGTTACACCCTAAAGCCTGAAACCTGA; ; Clone variation with respect to NM_000206.2;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000206 unedited; GTCATAATTGTATACGACNACTATAGGCGGCCGCGAAATTCGCACGAGGCGCCATGTTGA; AGCCATCATTACCATTCACATCCCTCTTATTCCTGCAGCTGCCCCTGCTGGGAGTGGGGC; TGAACACGACAATTCTGACGCCCAATGGGAATGAAGACACCACAGCTGATTTCTTCCTGA; CCACTATGCCCACTGACTCCCTCAGTGTTTCCACTCTGCCCCTCCCAGAGGTTCAGAGTT; TTGTGTTCAATGTCGAGTACATGAATTGCACTTGGAACAGCAGCTCTGAGCCCCATCCTA; CCAACCTCACTCTGCATTATTGGTACAAGAACTCGGATAATGATAAAGTCCAGAAGTGCA; GCCACTATCTATTCTCTGAAGAAATCACTTCTGGCTGTCAGTTGCAAAAAAAGGAGATCC; ACCTCTACCAAACATTTGTTGTTCAGCTCCAGGACCCACGGGAACCCATGATACAGGCCA; CACAGATGCTAAAACTGCAGAATCTGGTGATCCCCTGGGCTCCAGATAACCTAACACTTC; ACAAACTGAGTGAATCCCAGCTAGAACTGAACTGGAACAACAGATTCTTGAACCACTGTT; TGGAGCACTTGGTGCAGTACCGGACTGACTGGGACCACAGCTGGACTGAACAATCAGTGG; ATTATAGACATAAGTTCTCCTTGCCTAGTGTGGATGGGCAGAAACGCTACACGTTTCGTG; TTCGGAGCCGCTCTATCCACTCTGTGGAAGTGCTCACATTGGAGTGAATGGAGCCACCCA; ATCCACTGGGGGAGCAATACTTTCAAAGAGATNCTTTCCTGTNTGCATTGGAAGCCGAAG; TTATCTCTAGTGGCTCCATGAGATAGATATCANNNCTCTCTGAGTGTATTTCTGGCTGGA; ACGGACGATGCCCCNGATTNCCACCCTGAGATCTANAGGATCTTTTACTGATACANCGGA; ACTTTCGCA;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000206 unedited; NNNNGGTTTCTGTGNACCGCGGCCCGCTTTCTANGATCGAGTTTTTTCTTTTTTTTTTTT; TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGGTGATTATCAACAGAAACTTTTTTTT; TCATCGGTTCAGGAACAATCGGAGGGTAAATGGAAAAAGGAAGGGAGGGAAAAAGGGAGG; GAGGAAAAATCCTGCCAAAAGGAAGGGCCCCACTGTGTTTTTAAAAAAACTGTTCGGGGC; AAAAGGGTAATTTTCAAGTGGGGAATGCCCAATGAAGGGGTGCTTACCTGGGGGCCCAAA; ATTCCAAATCAACCCCAGTGGGGTGAGGTGAGTTTTAAACCCAGGTGGGTTGAATGAAGG; AAAGTTAGTTCCCCTTAGGGCTACCGGACCCTGGGGTTCTTCTGTCAAAGGATTGGGGTT; CAGGTTTCAGGCTTTAGGGTGTAACATGGGGGGGCCCAATAGGGGCTATTCTGGTTGCAT; GGGGAGGCCCCAGGCCCCTCCCCAAGGGCCCCTCCTTTTGGGGGAATCTCACTGACCAGG; CAAAGTCCTTCACTGTAGTCTGGCTGCAGACTCTCAACCAGTCCCTTAAACCACCACTCC; AGGCCGAAAAGTTCCCGTGGTATTCAGTAACAAGATCCTCTAGGTTCTTCAGGGTGGGAA; TTCGGGGCATCGTCCGTTCCAGCCAGAAAACACACCGAGAAGGCTGGTAATTCATCCCCT; GGAGCCAACAGAGATAACCACGGCTTTCAATGCAAACAGGAAAGGATTCCTCTTTTGAGA; TTTTGCTCCCCCATGGGATTGGGTGGCTCCATTCACTCCAATGCTGGACCCCTTTCCCAG; AATGGGGTAAAAGCCGCTCTCCAACACCAACGTTTTATCGTT;
• Restriction Sites: NotI-NotI
• ACCN: NM_000206
• Insert Size: 1500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_000206.1, NP_000197.1
• RefSeq Size: 1451 bp
• RefSeq ORF: 1110 bp
• Locus ID: 3561
• UniProt ID: P31785
• Cytogenetics: Xq13.1
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Endocytosis, Jak-STAT signaling pathway, Primary immunodeficiency
• Summary: The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder. [provided by RefSeq, Mar 2010]