BAAT1 (BRAT1) (NM_152743) Human Tagged ORF Clone Lentiviral Particle
SKU
RC204822L3V
Lenti ORF particles, BRAT1 (Myc-DDK tagged) - Human BRCA1-associated ATM activator 1 (BRAT1), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | BAAT1 |
Synonyms | BAAT1; C7orf27; NEDCAS; RMFSL |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC204822).
|
ACCN | NM_152743 |
ORF Size | 2463 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_152743.2, NP_689956.1 |
RefSeq Size | 3013 bp |
RefSeq ORF | 2466 bp |
Locus ID | 221927 |
UniProt ID | Q6PJG6 |
Cytogenetics | 7p22.3 |
MW | 88 kDa |
Summary | The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM. [provided by RefSeq, Mar 2012] |
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