alpha Tubulin (TUBA3C) (NM_079836) Human Tagged ORF Clone Lentiviral Particle
SKU
RC204072L3V
Lenti ORF particles, TUBA3C (Myc-DDK tagged) - Human tubulin, alpha 3c (TUBA3C), transcript variant 2, 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | alpha Tubulin |
Synonyms | bA408E5.3; TUBA2; tubulin, alpha 2; tubulin, alpha 3c |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC204072).
|
ACCN | NM_079836 |
ORF Size | 1254 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_079836.1, NP_524575.1 |
RefSeq Size | 1408 bp |
RefSeq ORF | 1256 bp |
Locus ID | 7278 |
Cytogenetics | 13q12.11 |
Protein Families | Druggable Genome, Stem cell - Pluripotency |
Protein Pathways | Gap junction, Pathogenic Escherichia coli infection |
MW | 46.1 kDa |
Summary | Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene is an alpha tubulin gene that encodes a protein 99% identical to the mouse testis-specific Tuba3 and Tuba7 gene products. This gene is located in the 13q11 region, which is associated with the genetic diseases Clouston hidrotic ectodermal dysplasia and Kabuki syndrome. [provided by RefSeq, Jul 2008] |
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