alpha Tubulin (TUBA3C) (NM_079836) Human Untagged Clone

SKU SC123106

TUBA3C (untagged)-Human tubulin, alpha 3c (TUBA3C), transcript variant 2

Product Data

• Type: Human Untagged Clone
• Target Symbol: alpha Tubulin
• Synonyms: bA408E5.3; TUBA2; tubulin, alpha 2; tubulin, alpha 3c
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_079836 edited; GTTGAGGTCAAGTAGTAGCGTTGGGCTGCGGCAGCGGAGGAGCTCAACATGCGTGAGTGT; ATCTCTATCCACGTGGGGCAGGCAGGAGTCCAGATCGGCAATGCCTGCTGGGAACTGTAC; TGCCTGGAACATGGAATTCAGCCCGATGGTCAGATGCCAAGTGATAAAACCATTGGTGGT; GGGGACGACTCCTTCAACACGTTCTTCAGTGAGACTGGAGCTGGCAAGCACGTGCCCAGA; GCAGTGTTTGTGGACCTGGAGCCCACTGTGGTCGATGAAGTGCGCACAGGAACCTATAGG; CAGCTCTTCCACCCAGAGCAGCTGATCACCGGGAAGGAAGATGCGGCCAATAATTACGCC; AGAGGCCATTACACCATCGGCAAGGAGATCGTCGACCTGGTCCTGGACCGGATCCGCAAA; CTGGCGGATCTGTGCACGGGACTGCAGGGCTTCCTCATCTTCCACAGTTTTGGGGGTGGC; ACTGGCTCTGGGTTCGCATCTCTGCTCATGGAGCGGCTCTCAGTGGATTACGGCAAGAAG; TCCAAGCTAGAATTTGCCATTTACCCAGCCCCCCAGGTCTCCACGGCCGTGGTGGAGCCC; TACAACTCCATCCTGACCACCCACACGACCCTGGAACATTCTGACTGTGCCTTCATGGTC; GACAATGAAGCCATCTATGACATATGTCGGCGCAACCTGGACATCGAGCGTCCCACGTAC; ACCAACCTCAATCGCCTGATTGGGCAGATCGTGTCCTCCATCACGGCCTCCCTGCGATTT; GACGGGGCCCTGAATGTGGACTTGACGGAATTCCAGACCAACCTAGTGCCGTACCCCCGC; ATCCACTTCCCCCTGGCCACCTACGCCCCGGTCATCTCAGCCGAGAAGGCCTACCACGAG; CAGCTGTCCGTGGCTGAGATCACCAATGCCTGCTTCGAGCCAGCCAATCAGATGGTCAAG; TGTGACCCTCGCCACGGCAAGTACATGGCCTGCTGCATGTTGTACAGGGGGGATGTGGTC; CCGAAAGATGTCAACGCGGCCATCGCCACCATCAAGACCAAGCGCACCATCCAGTTTGTA; GATTGGTGCCCAACTGGATTTAAGGTGGGCATTAACTACCAGCCCCCCACGGTGGTCCCT; GGGGGAGACCTGGCCAAGGTGCAGCGGGCTGTGTGCATGCTGAGCAACACCACGGCCATC; GCGGAGGCCTGGGCTCGCCTGGACCTGGCAGCTCTGGAGAAGGATTATGAAGAGGTGGGC; GTGGATTCCGTGGAAGCCGAGGCTGAAGAAGGTGAAGAATACTGAGGGGAGGGTGTGGTG; GGTTCTCCACTCCACTGCCACCCCCAGCGTGGCTGCTTTCAAGTTCTTTGCAATTAAAGG; TTCTGTATAAAAAAAAAAAAAAAAAAA;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_079836 unedited; GGACCGCGCAATTCGGCACGAGGGTTGAGGTCAAGTAGTAGCGTTGGGCTGCGGCAGCGG; AGGAGCTCAACATGCGTGAGTGTATCTCTATCCACGTGGGGCAGGCAGGAGTCCAGATCG; GCAATGCCTGCTGGGAACTGTACTGCCTGGAACATGGAATTCAGCCCGATGGTCAGATGC; CAAGTGATAAAACCATTGGTGGTGGGGACGACTCCTTCAACACGTTCTTCAGTGAGACTG; GAGCTGGCAAGCACGTGCCCAGAGCAGTGTTTGTGGACCTGGAGCCCACTGTGGTCGATG; AAGTGCGCACAGGAACCTATAGGCAGCTCTTCCACCCAGAGCAGCTGATCACCGGGAAGG; AAGATGCGGCCAATAATTACGCCAGAGGCCATTACACCATCGGCAAGGAGATCGTCGACC; TGGTCCTGGACCGGATCCGCAAACTGGCGGATCTGTGCACGGGACTGCAGGGCTTCCTCA; TCTTCCACAGTTTTGGGGGTGGCACTGGCTCTGGGTTCGCATCTCTGCTCATGGAGCGGC; TCTCAGTGGATTACGGCAAGAAGTCCAAGCTAGAATTTGCCATTTACCCAGCCCCCCAGG; TCTCCACGGCCGTGGTGGAGCCCTACAACTCCATCCTGACCACCCACACGACCCTGGAAC; ATTCTGACTGTGCCTTCATGGTCGACAATGAAGCCATCTATGACATATGTCGGCGCAACC; TGGACATCGAGCGTCCCACGTACACCAACCTCAATCGCCTGATTGGGCAGATCGTGTCCT; CCATCACGGCCTCCCTGCGATTTGACGGGGCCCTGAATAGTGACTT;
• Restriction Sites: Please inquire
• ACCN: NM_079836
• Insert Size: 1416 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_079836.1, NP_524575.1
• RefSeq Size: 1408 bp
• RefSeq ORF: 1257 bp
• Locus ID: 7278
• Cytogenetics: 13q12.11
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Gap junction, Pathogenic Escherichia coli infection
• Summary: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene is an alpha tubulin gene that encodes a protein 99% identical to the mouse testis-specific Tuba3 and Tuba7 gene products. This gene is located in the 13q11 region, which is associated with the genetic diseases Clouston hidrotic ectodermal dysplasia and Kabuki syndrome. [provided by RefSeq, Jul 2008]; Transcript Variant: This variant (2) uses alternative splicing, which results in a missing internal segment compared to variant 1. The encoded isoform (2) has identical termini to the full-length isoform but is missing an internal 32 residues near the C-terminus.