SIAH2 (NM_005067) Human Tagged ORF Clone Lentiviral Particle

SKU RC203802L3V

Lenti ORF particles, SIAH2 (Myc-DDK tagged) - Human seven in absentia homolog 2 (Drosophila) (SIAH2), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: SIAH2
• Synonyms: hSiah2
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC203802).
• ACCN: NM_005067
• ORF Size: 972 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_005067.5
• RefSeq Size: 2632 bp
• RefSeq ORF: 975 bp
• Locus ID: 6478
• UniProt ID: O43255
• Cytogenetics: 3q25.1
• Domains: Sina
• Protein Families: Druggable Genome, Transcription Factors
• MW: 34.4 kDa
• Summary: This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia. [provided by RefSeq, Jul 2008]