LMBR1 (NM_022458) Human Tagged ORF Clone Lentiviral Particle

SKU RC203703L3V

Lenti ORF particles, LMBR1 (Myc-DDK tagged) - Human limb region 1 homolog (mouse) (LMBR1), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: LMBR1
• Synonyms: ACHP; C7orf2; DIF14; LSS; PPD2; THYP; TPT; ZRS
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC203703).
• ACCN: NM_022458
• ORF Size: 1470 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_022458.3
• RefSeq Size: 4909 bp
• RefSeq ORF: 1473 bp
• Locus ID: 64327
• UniProt ID: Q8WVP7
• Cytogenetics: 7q36.3
• Domains: LMBR1, YdjC
• Protein Families: Transmembrane
• MW: 55.1 kDa
• Summary: This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression. [provided by RefSeq, Jul 2008]