Treacher Collins syndrome protein (TCOF1) (NM_001008657) Human Tagged ORF Clone Lentiviral Particle

SKU RC203644L3V

Lenti ORF particles, TCOF1 (Myc-DDK tagged) - Human Treacher Collins-Franceschetti syndrome 1 (TCOF1), transcript variant 3, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Treacher Collins syndrome protein
• Synonyms: MFD1; TCS; TCS1; treacle
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC203644).
• ACCN: NM_001008657
• ORF Size: 2874 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001008657.1
• RefSeq Size: 3877 bp
• RefSeq ORF: 2877 bp
• Locus ID: 6949
• UniProt ID: Q13428
• Cytogenetics: 5q32-q33.1
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• MW: 96.8 kDa
• Summary: This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]