PDE6D (NM_002601) Human Tagged ORF Clone Lentiviral Particle

SKU RC203172L3V

Lenti ORF particles, PDE6D (Myc-DDK tagged) - Human phosphodiesterase 6D, cGMP-specific, rod, delta (PDE6D), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: PDE6D
• Synonyms: JBTS22; PDED
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC203172).
• ACCN: NM_002601
• ORF Size: 450 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_002601.2
• RefSeq Size: 1214 bp
• RefSeq ORF: 453 bp
• Locus ID: 5147
• UniProt ID: O43924
• Cytogenetics: 2q37.1
• Protein Pathways: Progesterone-mediated oocyte maturation, Purine metabolism
• MW: 17.4 kDa
• Summary: This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants. [provided by RefSeq, Mar 2014]