ATP dependent metalloprotease YME1L1 (YME1L1) (NM_139313) Human Tagged ORF Clone Lentiviral Particle

SKU RC203167L3V

Lenti ORF particles, YME1L1 (Myc-DDK tagged) - Human YME1-like 1 (S. cerevisiae) (YME1L1), nuclear gene encoding mitochondrial protein, transcript variant 2, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: ATP dependent metalloprotease YME1L1
• Synonyms: FTSH, MEG4, PAMP, YME1L
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC203167).
• ACCN: NM_139313
• ORF Size: 2220 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_139313.1, NP_647474.1
• RefSeq Size: 2584 bp
• RefSeq ORF: 2222 bp
• Locus ID: 10730
• Cytogenetics: 10p12.1
• Domains: AAA, Peptidase_M41
• Protein Families: Druggable Genome, Protease
• MW: 82.7 kDa
• Summary: The protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]