Butyrylcholinesterase (BCHE) (NM_000055) Human Tagged ORF Clone Lentiviral Particle
SKU
RC202198L3V
Lenti ORF particles, BCHE (Myc-DDK tagged) - Human butyrylcholinesterase (BCHE), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | Butyrylcholinesterase |
Synonyms | BCHED; CHE1; CHE2; E1 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC202198).
|
ACCN | NM_000055 |
ORF Size | 1806 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_000055.1 |
RefSeq Size | 2461 bp |
RefSeq ORF | 1809 bp |
Locus ID | 590 |
UniProt ID | P06276 |
Cytogenetics | 3q26.1 |
Domains | COesterase |
Protein Families | Druggable Genome, Transmembrane |
MW | 68.4 kDa |
Summary | This gene encodes a cholinesterase enzyme and member of the type-B carboxylesterase/lipase family of proteins. The encoded enzyme exhibits broad substrate specificity and is involved in the detoxification of poisons including organophosphate nerve agents and pesticides, and the metabolism of drugs including cocaine, heroin and aspirin. Humans homozygous for certain mutations in this gene exhibit prolonged apnea after administration of the muscle relaxant succinylcholine. [provided by RefSeq, Jul 2016] |
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