n-Myc (MYCN) (NM_005378) Human Tagged ORF Clone Lentiviral Particle
SKU
RC201241L1V
Lenti ORF particles, MYCN (Myc-DDK tagged) - Human v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) (MYCN), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | n-Myc |
Synonyms | bHLHe37; MODED; N-myc; NMYC; ODED |
Vector | pLenti-C-Myc-DDK |
Mammalian Cell Selection | None |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC201241).
|
ACCN | NM_005378 |
ORF Size | 1392 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_005378.4 |
RefSeq Size | 2736 bp |
RefSeq ORF | 1395 bp |
Locus ID | 4613 |
UniProt ID | P04198 |
Cytogenetics | 2p24.3 |
Domains | HLH, Myc_N_term |
Protein Families | Druggable Genome, Transcription Factors |
MW | 49.6 kDa |
Summary | This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014] |
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