NCF2 (NM_000433) Human Tagged ORF Clone Lentiviral Particle

SKU RC200704L1V

Lenti ORF particles, NCF2 (Myc-DDK tagged) - Human neutrophil cytosolic factor 2 (NCF2), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: NCF2
• Synonyms: NCF-2; NOXA2; P67-PHOX; P67PHOX
• Vector: pLenti-C-Myc-DDK
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200704).
• ACCN: NM_000433
• ORF Size: 1578 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_000433.2
• RefSeq Size: 2406 bp
• RefSeq ORF: 1581 bp
• Locus ID: 4688
• UniProt ID: P19878
• Cytogenetics: 1q25.3
• Domains: PB1, SH3, TPR
• Protein Families: Druggable Genome
• Protein Pathways: Leukocyte transendothelial migration
• MW: 59.6 kDa
• Summary: This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2010]