NPC2 (NM_006432) Human Tagged ORF Clone Lentiviral Particle

SKU RC200282L4V

Lenti ORF particles, NPC2 (mGFP-tagged) - Human Niemann-Pick disease, type C2 (NPC2), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: NPC2
• Synonyms: EDDM1; HE1
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200282).
• ACCN: NM_006432
• ORF Size: 453 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_006432.3
• RefSeq Size: 921 bp
• RefSeq ORF: 456 bp
• Locus ID: 10577
• UniProt ID: P61916
• Cytogenetics: 14q24.3
• Domains: ML
• Protein Families: Druggable Genome, Secreted Protein
• MW: 16.6 kDa
• Summary: This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy. [provided by RefSeq, Jul 2008]