Unc13b (NM_021468) Mouse Tagged ORF Clone Lentiviral Particle

SKU MR222713L3V

Lenti ORF particles, Unc13b (Myc-DDK-tagged) - Mouse unc-13 homolog B (C. elegans) (Unc13b), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Unc13b
• Synonyms: Munc13-1; Munc13-2; Unc13a; Unc13h1; Unc13h2
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR222713).
• ACCN: NM_021468
• ORF Size: 4806 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_021468.3, NP_067443.2
• RefSeq Size: 6426 bp
• RefSeq ORF: 4809 bp
• Locus ID: 22249
• UniProt ID: Q9Z1N9
• Cytogenetics: 4 A5
• Summary: Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP) (By similarity). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses.[UniProtKB/Swiss-Prot Function]