Sh3pxd2a (NM_001164717) Mouse Tagged ORF Clone Lentiviral Particle

SKU MR216063L3V

Lenti ORF particles, Sh3pxd2a (Myc-DDK-tagged) - Mouse SH3 and PX domains 2A (Sh3pxd2a), transcript variant 2, 200ul, >10^7 TU/mL

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Sh3pxd2a
• Synonyms: 2310014D11Rik; AA589508; AI256723; AI413738; C230050L11; EG329070; Fish; Gm5098; Sh3md1
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR216063).
• ACCN: NM_001164717
• ORF Size: 3288 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001164717.1, NP_001158189.1
• RefSeq Size: 10380 bp
• RefSeq ORF: 3291 bp
• Locus ID: 14218
• UniProt ID: O89032
• Cytogenetics: 19 C3
• Summary: Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide (By similarity).[UniProtKB/Swiss-Prot Function]