Rfx2 (NM_009056) Mouse Tagged ORF Clone Lentiviral Particle

SKU MR210076L3V

Lenti ORF particles, Rfx2 (Myc-DDK-tagged) - Mouse regulatory factor X, 2 (influences HLA class II expression) (Rfx2), transcript variant 2, 200ul, >10^7 TU/mL

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Rfx2
• Synonyms: 5430432H19Rik
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR210076).
• ACCN: NM_009056
• ORF Size: 2076 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_009056.2, NP_033082.1
• RefSeq Size: 3278 bp
• RefSeq ORF: 2079 bp
• Locus ID: 19725
• UniProt ID: P48379
• Cytogenetics: 17 29.5 cM
• Summary: Transcription factor that acts as a key regulator of spermatogenesis (PubMed:26248850, PubMed:26162102, PubMed:26853561). Acts by regulating expression of genes required for the haploid phase during spermiogenesis, such as genes required for cilium assembly and function (PubMed:26162102, PubMed:26853561). Recognizes and binds the X-box, a regulatory motif with DNA sequence 5'-GTNRCC(0-3N)RGYAAC-3' present on promoters (PubMed:15229132, PubMed:26162102). Probably activates transcription of the testis-specific histone gene HIST1H1T (PubMed:15229132).[UniProtKB/Swiss-Prot Function]