Arntl (NM_007489) Mouse Tagged ORF Clone Lentiviral Particle
SKU
MR209553L3V
Lenti ORF particles, Arntl (Myc-DDK-tagged) - Mouse aryl hydrocarbon receptor nuclear translocator-like (Arntl), 200ul, >10^7 TU/mL
Product Data | |
Type | Mouse Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | Arntl |
Synonyms | Arnt3; bHLHe5; Bmal1; BMAL1b; bmal1b'; MOP3 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(MR209553).
|
ACCN | NM_007489 |
ORF Size | 1878 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_007489.3 |
RefSeq Size | 2921 bp |
RefSeq ORF | 1881 bp |
Locus ID | 11865 |
UniProt ID | Q9WTL8 |
Cytogenetics | 7 59.17 cM |
Summary | The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with Clock. This heterodimer binds E-box enhancer elements upstream of Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2) genes and activates transcription of these genes. Per and Cry proteins heterodimerize and repress their own transcription by interacting in a feedback loop with Clock/Arntl complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2014] |
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