Il15 (NM_008357) Mouse Tagged ORF Clone Lentiviral Particle
SKU
MR201274L1V
Lenti ORF particles, Il15 (Myc-DDK-tagged) - Mouse interleukin 15 (Il15), 200ul, >10^7 TU/mL
Product Data | |
Type | Mouse Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | Il15 |
Synonyms | AI503618; IL-15 |
Vector | pLenti-C-Myc-DDK |
Mammalian Cell Selection | None |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(MR201274).
|
ACCN | NM_008357 |
ORF Size | 486 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_008357.1 |
RefSeq Size | 1297 bp |
RefSeq ORF | 489 bp |
Locus ID | 16168 |
UniProt ID | P48346 |
Cytogenetics | 8 39.33 cM |
Summary | This gene encodes a a pleiotropic cytokine of the interleukin family of proteins that plays important roles in the innate and adaptive cell homeostasis, as well as peripheral immune function. The encoded protein undergoes proteolytic processing to generate a mature cytokine that stimulates the proliferation of natural killer cells. The transgenic mice overexpressing the encoded protein exhibit an increase in the number of memory CD8+ T cells in a naive state and enhanced protection against bacterial infections. Mice lacking the encoded protein exhibit impaired protection against a strain of attenuated Mycobacterium. [provided by RefSeq, Aug 2016] |
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