Atg12 (NM_026217) Mouse Tagged ORF Clone Lentiviral Particle
SKU
MR200886L3V
Lenti ORF particles, Atg12 (Myc-DDK-tagged) - Mouse autophagy-related 12 (yeast) (Atg12), 200ul, >10^7 TU/mL
Product Data | |
Type | Mouse Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | Atg12 |
Synonyms | 4931423H11Rik; A330058M13Rik; Apg12l; Atg12l |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(MR200886).
|
ACCN | NM_026217 |
ORF Size | 423 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_026217.1 |
RefSeq Size | 2459 bp |
RefSeq ORF | 426 bp |
Locus ID | 67526 |
UniProt ID | Q9CQY1 |
Cytogenetics | 18 C |
Summary | Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes.[UniProtKB/Swiss-Prot Function] |
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