C15orf38 (ARPIN) (NM_182616) Human Untagged Clone

SKU SC321902

C15orf38 (untagged)-Human chromosome 15 open reading frame 38 (C15orf38)

Product Data

• Type: Human Untagged Clone
• Target Symbol: C15orf38
• Synonyms: C15orf38
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_182616.1 CGCGGGTCCCCGCGCGTCCTGCAGCACTTCCCGCGCCGCGCCCCCAGCCCAGTGCGCCGG; CTCTGTGCCGGGGTGCCCGGGCGGTCGGGAGAATGAGCCGCATCTACCACGACGGCGCGC; TCCGGAACAAGGCGGTGCAGAGCGTCCGGCTGCCAGGGGCCTGGGACCCCGCCGCCCACC; AGGGGGGAAATGGTGTCCTGCTGGAGGGAGAACTGATCGATGTATCTCGGCACAGCATCT; TGGACACTCATGGCAGGAAGGAGCGCTACTACGTGCTGTATATCCGGCCCAGTCACATCC; ATCGCCGTAAATTCGACGCCAAGGGAAATGAAATCGAGCCCAACTTCAGCGCCACCAGGA; AGGTGAACACGGGCTTCCTCATGTCGTCCTACAAGGTGGAAGCCAAGGGGGACACTGACA; GGCTCACGCCCGAGGCGCTGAAGGGGCTGGTCAACAAGCCAGAGCTGCTCGCGCTGACAG; AGAGCCTCACCCCCGACCACACAGTGGCGTTCTGGATGCCCGAGTCAGAGATGGAGGTGA; TGGAACTCGAGCTGGGGGCCGGGGTACGGCTGAAGACTCGGGGCGATGGTCCCTTCCTGG; ATTCATTGGCCAAACTTGAGGCTGGAACAGTGACCAAGTGTAATTTCACTGGTGATGGAA; AGACAGGGGCATCCTGGACAGACAACATCATGGCCCAAAAGTGTTCGAAGGGGGCTGCAG; CGGAGATCCGAGAGCAGGGGGATGGGGCAGAGGACGAGGAGTGGGATGACTGAGGGACGT; GGCTGCCTCTGGGGGCACCAGCACCTTCTGTAGCATTGTGGAACATTTCTTCCATGAACT; TCTACTCTGGAGCTGGAGAGAACAGTCTGCCAAGTCTTACCTGGTTCTTCCCCATAGCCA; CCTTGGAATACTCTTTGAACAAGCTCTGCTAAAACCAAACCCATGACCACTGTGTTGGTG; GTGGGGCCTCATGCTGTGGCTCAGGGAGGGCCCCTCCCTGCATGTGAGTCTAGCCTTCCT; AGACATTACATGATGACCCTTTAAAAAAAAATTAGAGATGGAGGTCTCACTGTGTTGCCC; AGGCTGATCTCGAACTCCTGGACTCAAGCGATCCACCCACCTCCACCTCCCAAGGTGTTG; GGATTACAGGCGTGAGCCACCGCACCCAGCCTCATGTTGACCCTGGCCCTGGATAGCAGC; TTTGTTTGTAGAGGCAGGTGGTGGGAGAGACCCTAGGACAGCCTGAGAGTAACTGGACCT; GGTATTGGTGCGGAGTGGGGAATATCCCTTGTCTAAATGCAGAGCAGCTGAGAGAAGTTA; GCGGGGCTCTTCCTCCGTTCTCATTGTTTCCTGCTTTCCTTCCCCACCCACCCCTTCCTC; AGCACTCTGTGTTGTAGCCTGTACTATCCTGCTTCAAGCCTCCGTGTCCCTTGTACCTTC; CCCCTACCTTGAGTTGCCAGTTCTTTACTCCCTCAAATGTTCCCATGCCACCTCTGGGGT; TTCTGTTATCTGACATCCCTGGCTGCTTTCCTGGTAGATGCCATTCCCAGAGAGGCCAAC; AGCGTTCCCAGGCGTGGCTGGCTGGTCCGCATCTCTCAGACTCACTCTGCCAGGCTACAG; TTTTGAGAATACCTTTTTTGTTGTTGTTTTGTACCTGGAGAACTTTTTATGAATGAGTAA; ATCTTCAGAAAGGAATTCCTCCACCCTTACTGGGTTATTGTCAGGTGTAAACGGCCTTTC; AGCTGAGCAATGTTCCTATGAGAAGGAAGCCATTTCTCTTGGCTCATGAACACTGCCTTT; TGGGTAGTATACCCACACCCAGATCTGTGAAGAGACCTGGAATTGAAGTCTCCATGTCGT; CAGGACTTGGTGGCATGTGGATCTTGCTTGACTTGGGAAAAGAGAGGGTGGTGGTGAACT; AATAATTATGGAGTCCCCCTAATGTGTCGAACACAATGCTAGATGATTAAAAAAAAAAAA; AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA; AAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_182616
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_182616.1, NP_872422.1
• RefSeq Size: 2065 bp
• RefSeq ORF: 681 bp
• Locus ID: 348110
• UniProt ID: Q7Z6K5
• Cytogenetics: 15q26.1
• Summary: Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors. Participates in an incoherent feedforward loop at the lamellipodium tip where it inhibits the ARP2/2 complex in response to Rac signaling and where Rac also stimulates actin polymerization through the WAVE complex. Involved in steering cell migration by controlling its directional persistence.[UniProtKB/Swiss-Prot Function]; Transcript Variant: This variant (1) represents the shorter transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.