XPO6 (NM_015171) Human Untagged Clone

SKU SC304247

XPO6 (untagged)-Human exportin 6 (XPO6)

Product Data

• Type: Human Untagged Clone
• Target Symbol: XPO6
• Synonyms: EXP6; RANBP20
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >SC304247 representing NM_015171.; Blue=Insert sequence Red=Cloning site Green=Tag(s); ; GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG; GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC; ATGGCATCTGAAGAAGCCTCTCTCAGGGCATTGGAAAGTCTGATGACAGAATTTTTTCACGATTGTACA; ACCAATGAAAGAAAACGTGAGATAGAGGAGCTTCTTAATAACTTTGCCCAGCAAATAGGAGCCTGGAGA; TTCTGCCTGTACTTTCTCTCCAGCACTAGGAATGACTATGTAATGATGTACAGTTTAACAGTTTTTGAG; AATCTGATCAATAAAATGTGGCTTGGGGTCCCATCTCAGGATAAGATGGAAATCCGTAGCTGTCTGCCC; AAACTCCTTTTGGCTCACCATAAAACCTTACCTTACTTTATCCGGAACAAGCTCTGCAAAGTTATTGTT; GATATTGGACGTCAGGATTGGCCCATGTTCTACCACGACTTTTTTACTAACATTTTACAGTTGATCCAG; TCCCCTGTGACAACCCCCCTTGGGCTGATCATGTTGAAGACAACTTCAGAAGAGCTGGCTTGTCCCCGT; GAGGACCTCAGTGTGGCTCGGAAGGAGGAGTTGCGGAAGCTGCTACTGGACCAGGTGCAGACAGTGCTT; GGGCTACTGACAGGTATCTTGGAGACTGTCTGGGACAAACACAGTGTTACTGCTGCCACTCCACCACCA; TCCCCGACCTCAGGAGAAAGTGGTGACTTACTGAGTAACCTGTTGCAGAGTCCCAGTTCAGCCAAACTG; TTGAATCAGCCAATTCCCATCCTTGATGTGGAGAGTGAGTATATCTGTTCCCTGGCTTTGGAGTGCCTG; GCCCATCTCTTCAGTTGGATTCCTCTGTCTGCCAGCATCACCCCATCCCTCCTTACCACCATCTTCCAC; TTTGCACGATTTGGCTGTGACATCCGGGCCAGAAAGATGGCGTCAGTTAACGGCAGCAGCCAGAACTGT; GTCTCGGGTCAGGAGCGCGGCCGGCTGGGGGTCCTGGCCATGTCCTGCATCAATGAACTCATGTCCAAG; AACTGTGTGCCTATGGAATTTGAGGAGTATTTACTGCGTATGTTCCAGCAGACTTTCTACCTCCTGCAG; AAAATCACCAAGGATAACAATGCCCACACAGTGAAGAGCAGGCTAGAAGAGCTCGATGAGAGCTATATC; GAGAAGTTTACTGACTTTCTTCGGCTCTTTGTGAGTGTTCACCTAAGAAGAATCGAGTCTTACTCCCAG; TTCCCTGTGGTGGAGTTTTTGACACTTTTGTTCAAGTACACATTTCATCAGCCTACTCATGAAGGTTAC; TTCTCTTGTTTGGATATCTGGACGCTGTTTTTGGACTATCTGACAAGTAAAATTAAAAGTCGTCTTGGA; GACAAGGAAGCAGTTCTCAACAGGTACGAAGATGCCCTGGTGCTCCTGCTCACAGAGGTGTTGAATCGA; ATCCAGTTCAGATACAACCAAGCCCAGCTGGAGGAGTTGGATGATGAGACTCTGGATGACGATCAGCAG; ACGGAGTGGCAGCGGTACTTACGGCAGAGCTTGGAGGTGGTGGCCAAAGTGATGGAGCTCCTGCCCACG; CACGCCTTCTCCACACTGTTCCCTGTTCTTCAGGACAATTTAGAAGTTTATTTGGGATTACAACAGTTT; ATAGTCACTTCAGGGTCAGGACACAGGTTGAACATCACGGCGGAGAACGACTGCCGGCGGCTGCACTGC; TCCCTGAGAGACTTGAGCTCCCTGCTGCAGGCCGTGGGCCGCCTGGCCGAGTACTTTATCGGGGATGTG; TTTGCTGCACGGTTCAATGATGCCCTCACAGTCGTGGAAAGGTTGGTCAAAGTCACTCTGTACGGATCT; CAGATAAAATTGTACAACATTGAAACTGCTGTGCCATCAGTATTGAAACCTGACCTCATTGATGTGCAT; GCTCAGTCCCTGGCTGCGCTGCAGGCTTACTCTCACTGGTTAGCACAGTATTGCAGTGAAGTTCACCGG; CAGAACACGCAGCAGTTCGTGACACTCATCTCTACTACCATGGATGCAATCACACCTCTAATCAGCACC; AAGGTCCAAGACAAGCTGCTGCTATCTGCGTGCCACTTACTGGTCTCACTGGCCACCACCGTGCGGCCC; GTCTTTCTGATCAGCATCCCTGCAGTGCAGAAAGTATTCAACAGAATCACTGATGCCTCTGCCCTGCGA; CTTGTCGATAAGGCCCAGGTGTTGGTGTGCCGAGCCCTCTCTAACATCTTGCTGCTTCCGTGGCCAAAC; CTTCCAGAGAATGAGCAGCAGTGGCCCGTGCGCTCCATCAACCACGCCAGCCTCATCTCTGCACTCTCC; CGGGACTATCGCAACCTGAAGCCCAGTGCTGTTGCCCCACAGAGAAAGATGCCACTGGATGACACCAAA; CTGATTATCCACCAGACACTCAGCGTCTTAGAAGATATTGTGGAGAATATCTCGGGGGAGTCCACCAAG; TCTCGACAGATTTGCTACCAGTCGCTGCAGGAATCTGTTCAGGTCTCCCTGGCCCTCTTTCCAGCTTTT; ATCCATCAGTCAGATGTGACTGATGAGATGCTGAGCTTCTTCCTCACTCTGTTTCGAGGCCTTAGAGTA; CAGATGGGTGTGCCTTTCACTGAGCAAATCATACAGACTTTCCTCAACATGTTTACCAGAGAGCAGTTA; GCCGAGAGCATCCTCCACGAGGGCAGCACAGGCTGCCGGGTGGTGGAGAAGTTTCTGAAGATCCTGCAG; GTGGTGGTCCAGGAGCCAGGCCAGGTGTTCAAGCCCTTCCTCCCCAGCATCATCGCCCTGTGCATGGAG; CAAGTGTATCCCATCATTGCCGAGCGTCCCTCCCCTGATGTGAAGGCCGAGCTGTTTGAGCTCCTTTTC; CGGACGCTCCATCACAACTGGAGGTACTTCTTCAAGTCCACCGTGCTGGCCAGTGTCCAGAGGGGGATC; GCTGAGGAGCAGATGGAGAATGAGCCCCAGTTCAGTGCCATCATGCAGGCTTTCGGACAGTCCTTTCTC; CAGCCCGACATCCACCTTTTTAAACAAAATCTCTTCTACTTGGAGACTCTCAACACCAAGCAGAAGCTG; TACCACAAGAAGATCTTCCGGACTGCCATGCTGTTCCAGTTTGTGAACGTGCTGCTCCAGGTCCTGGTC; CACAAGTCCCATGATCTTCTGCAGGAGGAGATTGGCATCGCCATCTACAACATGGCCTCAGTCGACTTT; GATGGCTTCTTTGCCGCCTTCCTCCCAGAGTTCCTGACCAGCTGTGATGGTGTGGATGCCAACCAGAAA; AGTGTGCTGGGGCGGAATTTCAAGATGGATCGGGACCTGCCCTCATTCACCCAGAATGTGCACAGGCTG; GTCAACGACCTGCGCTACTACAGACTCTGCAACGACAGCCTGCCCCCTGGCACTGTGAAGCTCTAG; ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT; TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC;
• Restriction Sites: SgfI-MluI
• ACCN: NM_015171
• Insert Size: 3378 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_015171.3
• RefSeq Size: 4504 bp
• RefSeq ORF: 3378 bp
• Locus ID: 23214
• UniProt ID: Q96QU8
• Cytogenetics: 16p12.1
• MW: 128.9 kDa
• Summary: The protein encoded by this gene is a member of the importin-beta family. Members of this family are regulated by the GTPase Ran to mediate transport of cargo across the nuclear envelope. This protein has been shown to mediate nuclear export of profilin-actin complexes. A pseudogene of this gene is located on the long arm of chromosome 14. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]; Transcript Variant: This variant (2) lacks an alternate exon in the 5' UTR and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is longer than isoform 1.