TRPM4 (NM_017636) Human Untagged Clone

SKU SC123991

TRPM4 (untagged)-Human transient receptor potential cation channel, subfamily M, member 4 (TRPM4), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: TRPM4
• Synonyms: EKVP6; hTRPM4; LTrpC4; PFHB1B; TRPM4B
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC123991 sequence for NM_017636 edited (data generated by NextGen Sequencing); ATGGTGGTGCCGGAGAAGGAGCAGAGCTGGATCCCCAAGATCTTCAAGAAGAAGACCTGC; ACGACGTTCATAGTTGACTCCACAGATCCGGGAGGGACCTTGTGCCAGTGTGGGCGCCCC; CGGACCGCCCACCCCGCAGTGGCCATGGAGGATGCCTTCGGGGCAGCCGTGGTGACCGTG; TGGGACAGCGATGCACACACCACGGAGAAGCCCACCGATGCCTACGGAGAGCTGGACTTC; ACGGGGGCCGGCCGCAAGCACAGCAATTTCCTCCGGCTCTCTGACCGAACGGATCCAGCT; GCAGTTTATAGTCTGGTCACACGCACATGGGGCTTCCGTGCCCCGAACCTGGTGGTGTCA; GTGCTGGGGGGATCGGGGGGCCCCGTCCTCCAGACCTGGCTGCAGGACCTGCTGCGTCGT; GGGCTGGTGCGGGCTGCCCAGAGCACAGGAGCCTGGATTGTCACTGGGGGTCTGCACACG; GGCATCGGCCGGCATGTTGGTGTGGCTGTACGGGACCATCAGATGGCCAGCACTGGGGGC; ACCAAGGTGGTGGCCATGGGTGTGGCCCCCTGGGGTGTGGTCCGGAATAGAGACACCCTC; ATCAACCCCAAGGGCTCGTTCCCTGCGAGGTACCGGTGGCGCGGTGACCCGGAGGACGGG; GTCCAGTTTCCCCTGGACTACAACTACTCGGCCTTCTTCCTGGTGGACGACGGCACACAC; GGCTGCCTGGGGGGCGAGAACCGCTTCCGCTTGCGCCTGGAGTCCTACATCTCACAGCAG; AAGACGGGCGTGGGAGGGACTGGAATTGACATCCCTGTCCTGCTCCTCCTGATTGATGGT; GATGAGAAGATGTTGACGCGAATAGAGAACGCCACCCAGGCTCAGCTCCCATGTCTCCTC; GTGGCTGGCTCAGGGGGAGCTGCGGACTGCCTGGCGGAGACCCTGGAAGACACTCTGGCC; CCAGGGAGTGGGGGAGCCAGGCAAGGCGAAGCCCGAGATCGAATCAGGCGTTTCTTTCCC; AAAGGGGACCTTGAGGTCCTGCAGGCCCAGGTGGAGAGGATTATGACCCGGAAGGAGCTC; CTGACAGTCTATTCTTCTGAGGATGGGTCTGAGGAATTCGAGACCATAGTTTTGAAGGCC; CTTGTGAAGGCCTGTGGGAGCTCGGAGGCCTCAGCCTACCTGGATGAGCTGCGTTTGGCT; GTGGCTTGGAACCGCGTGGACATTGCCCAGAGTGAACTCTTTCGGGGGGACATCCAATGG; CGGTCCTTCCATCTCGAAGCTTCCCTCATGGACGCCCTGCTGAATGACCGGCCTGAGTTC; GTGCGCTTGCTCATTTCCCACGGCCTCAGCCTGGGCCACTTCCTGACCCCGATGCGCCTG; GCCCAACTCTACAGCGCGGCGCCCTCCAACTCGCTCATCCGCAACCTTTTGGACCAGGCG; TCCCACAGCGCAGGCACCAAAGCCCCAGCCCTAAAAGGGGGAGCTGCGGAGCTCCGGCCC; CCTGACGTGGGGCATGTGCTGAGGATGCTGCTGGGGAAGATGTGCGCGCCGAGGTACCCC; TCCGGGGGCGCCTGGGACCCTCACCCAGGCCAGGGCTTCGGGGAGAGCATGTATCTGCTC; TCGGACAAGGCCACCTCGCCGCTCTCGCTGGATGCTGGCCTCGGGCAGGCCCCCTGGAGC; GACCTGCTTCTTTGGGCACTGTTGCTGAACAGGGCACAGATGGCCATGTACTTCTGGGAG; ATGGGTTCCAATGCAGTTTCCTCAGCTCTTGGGGCCTGTTTGCTGCTCCGGGTGATGGCA; CGCCTGGAGCCTGACGCTGAGGAGGCAGCACGGAGGAAAGACCTGGCGTTCAAGTTTGAG; GGGATGGGCGTTGACCTCTTTGGCGAGTGCTATCGCAGCAGTGAGGTGAGGGCTGCCCGC; CTCCTCCTCCGTCGCTGCCCGCTCTGGGGGGATGCCACTTGCCTCCAGCTGGCCATGCAA; GCTGACGCCCGTGCCTTCTTTGCCCAGGATGGGGTACAGTCTCTGCTGACACAGAAGTGG; TGGGGAGATATGGCCAGCACTACACCCATCTGGGCCCTGGTTCTCGCCTTCTTTTGCCCT; CCACTCATCTACACCCGCCTCATCACCTTCAGGAAATCAGAAGAGGAGCCCACACGGGAG; GAGCTAGAGTTTGACATGGATAGTGTCATTAATGGGGAAGGGCCTGTCGGGACGGCGGAC; CCAGCCGAGAAGACGCCGCTGGGGGTCCCGCGCCAGTCGGGCCGTCCGGGTTGCTGCGGG; GGCCGCTGCGGGGGGCGCCGGTGCCTACGCCGCTGGTTCCACTTCTGGGGCGCGCCGGTG; ACCATCTTCATGGGCAACGTGGTCAGCTACCTGCTGTTCCTGCTGCTTTTCTCGCGGGTG; CTGCTCGTGGATTTCCAGCCGGCGCCGCCCGGCTCCCTGGAGCTGCTGCTCTATTTCTGG; GCTTTCACGCTGCTGTGCGAGGAACTGCGCCAGGGCCTGAGCGGAGGCGGGGGCAGCCTC; GCCAGCGGGGGCCCCGGGCCTGGCCATGCCTCACTGAGCCAGCGCCTGCGCCTCTACCTC; GCCGACAGCTGGAACCAGTGCGACCTAGTGGCTCTCACCTGCTTCCTCCTGGGCGTGGGC; TGCCGGCTGACCCCGGGTTTGTACCACCTGGGCCGCACTGTCCTCTGCATCGACTTCATG; GTTTTCACGGTGCGGCTGCTTCACATCTTCACGGTCAACAAACAGCTGGGGCCCAAGATC; GTCATCGTGAGCAAGATGATGAAGGACGTGTTCTTCTTCCTCTTCTTCCTCGGCGTGTGG; CTGGTAGCCTATGGCGTGGCCACGGAGGGGCTCCTGAGGCCACGGGACAGTGACTTCCCA; AGTATCCTGCGCCGCGTCTTCTACCGTCCCTACCTGCAGATCTTCGGGCAGATTCCCCAG; GAGGACATGGACGTGGCCCTCATGGAGCACAGCAACTGCTCGTCGGAGCCCGGCTTCTGG; GCACACCCTCCTGGGGCCCAGGCGGGCACCTGCGTCTCCCAGTATGCCAACTGGCTGGTG; GTGCTGCTCCTCGTCATCTTCCTGCTCGTGGCCAACATCCTGCTGGTCAACTTGCTCATT; GCCATGTTCAGTTACACATTCGGCAAAGTACAGGGCAACAGCGATCTCTACTGGAAGGCG; CAGCGTTACCGCCTCATCCGGGAATTCCACTCTCGGCCCGCGCTGGCCCCGCCCTTTATC; GTCATCTCCCACTTGCGCCTCCTGCTCAGGCAATTGTGCAGGCGACCCCGGAGCCCCCAG; CCGTCCTCCCCGGCCCTCGAGCATTTCCGGGTTTACCTTTCTAAGGAAGCCGAGCGGAAG; CTGCTAACGTGGGAATCGGTGCATAAGGAGAACTTTCTGCTGGCACGCGCTAGGGACAAG; CGGGAGAGCGACTCCGAGCGTCTGAAGCGCACGTCCCAGAAGGTGGACTTGGCACTGAAA; CAGCTGGGACACATCCGCGAGTACGAACAGCGCCTGAAAGTGCTGGAGCGGGAGGTCCAG; CAGTGTAGCCGCGTCCTGGGGTGGGTGGCCGAGGCCCTGAGCCGCTCTGCCTTGCTGCCC; CCAGGTGGGCCGCCACCCCCTGACCTGCCTGGGTCCAAAGACTGA; ; Clone variation with respect to NM_017636.3;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_017636 unedited; AGGTCAGNAATTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGGCGGCCGC; GGCAGCATGGTGGTGCCGGAGAAGGAGCAGAGCTGGATCCCCAAGATCTTCAAGAAGAAG; ACCTGCACGACGTTCATAGTTGACTCCACAGATCCGGGAGGGACCTTGTGCCAGTGTGGG; CGCCCCCGGACCGCCCACCCCGCAGTGGCCATGGAGGATGCCTTCGGGGCAGCCGTGGTG; ACCGTGTGGGACAGCGATGCACACACCACGGAGAAGCCCACCGATGCCTACGGAGAGCTG; GACTTCACGGGGGCCGGCCGCAAGCACAGCAATTTCCTCCGGCTCTCTGACCGAACGGAT; CCAGCTGCAGTTTATAGTCTGGTCACACGCACATGGGGCTTCCGTGCCCCGAACCTGGTG; GTGTCAGTGCTGGGGGGATCGGGGGGCCCCGTCCTCCAGACCTGGCTGCAGGACCTGCTG; CGTCGTGGGCTGGTGCGGGCTGCCCAGAGCACAGGAGCCTGGATTGTCACTGGGGGTCTG; CACACGGGCATCGGCCGGCATGTTGGTGTGGCTGTACGGGACCATCAGATGGCCAGCACT; GGGGGCACCAAGGTGGTGGCCATGGGTGTGGCCCCCTGGGGTGTGGTCCGGAATAGAGAC; ACCCTCATCAACCCCAAAGGCTCGTTCCCTGCGAGGTACCCGTGGCGCCGTGACCCGGAA; GACGGGGTCCAGTTTTCCCTGGACTACCACTACTCGGCCCTCTTTCTGGTGGGAGACGGG; ACACACCGCTGCCCGGGGGGCGAGAACGGCTTCCGCTTCGCCTGGAATCCACATCTCACA; CCCAAAAACAGGCCTGGGAGGGACTGGAAATGACACCCTGTCCCGCTCCCCCGATTGATG; GGGATAAAAAAATTTAAT;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_017636 unedited; TCCGGGCCAGGAGAGGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGATCTGTTCAGG; AAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTT; TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCCCCCGGAAAGGGCTTTTTTTCCCC; AGTGGGAGAAATCTGTGAGTGGGGGGGGGTCTGGGGCCCCTGTTACCCCAGGGCCCCTGC; ACCCCCCAAATGGATAACGGCCCGGGTTCCAGGCCTTGATCCCCCCAGGCTGGGACTGGT; TCTGGGAGGACCCGGGCATGCTGTGTTTTGTAAGGATAACCCCCCCAAAGGGGGTCCTGA; CAGGGGCCCAAATGGACATGGGGCTCACCTCAGGGACAAGGCCCCCAGGTGGGGGGGCCG; AGGCCCAAATGACCCTTACTTTAGGACCAAAACCCCCGGGGGGGGCTTCTCCTTGAAGTC; CGCCAGCGGGGCTAATTTTTTGGACCCAGGCAGGTCAGGGGGGGGCGGCCCACCTGGGGG; CAACAAGGCAAAGCGGCTAAGGGCCTTGGCCACCCACCCAAGGACGCGGCTACACTGCTG; GACCTCCCGCTCCAGCATTTTGAGGCGCTGTTCGTACTCCGCGGAGGGTCCCAACTTGTT; TTAAGGGCCATGCCCACCTTTGGGGACGTGCGCTTAAGACGCTGGGAGTCGCTCTCCCGT; GTGTCCCTGCCGCGGCCG;
• Restriction Sites: Please inquire
• ACCN: NM_017636
• Insert Size: 4500 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_017636.2, NP_060106.2
• RefSeq Size: 4061 bp
• RefSeq ORF: 3645 bp
• Locus ID: 54795
• UniProt ID: Q8TD43
• Cytogenetics: 19q13.33
• Protein Families: Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane
• Summary: The protein encoded by this gene is a calcium-activated nonselective ion channel that mediates transport of monovalent cations across membranes, thereby depolarizing the membrane. The activity of the encoded protein increases with increasing intracellular calcium concentration, but this channel does not transport calcium. [provided by RefSeq, Mar 2016]; Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).