DDIT3 (NM_004083) Human Untagged Clone
DDIT3 (untagged)-Human DNA-damage-inducible transcript 3 (DDIT3), transcript variant 5
|Product Name||DDIT3 (NM_004083) Human Untagged Clone|
|Synonyms||CEBPZ; CHOP; CHOP-10; CHOP10; GADD153|
Fully Sequenced ORF
>NCBI ORF sequence for NM_004083, the custom clone sequence may differ by one or more nucleotides
5' Read Nucleotide Sequence
>OriGene 5' read for NM_004083 unedited
|ORF Size||510 bp|
|OTI Disclaimer||Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).|
|Product Components||The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.|
|Protein Families||Transcription Factors, Druggable Genome|
|Protein Pathways||MAPK signaling pathway|
|Gene Summary||This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010].
Transcript Variant: This variant (5) lacks an internal segment in the 5' region, resulting in a downstream AUG start codon, as compared to variant 1. The resulting isoform (2) is shorter at the N-terminus, as compared to isoform 1.
|cDNA Clone Resources|