c-Myc(MYC) (NM_002467) Human Untagged Clone

CAT#: SC112715

MYC (untagged)-Human v-myc myelocytomatosis viral oncogene homolog (avian) (MYC)

USD 196.00


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Size
    • 10 ug

Product images

Specifications

Product Data
Product Name c-Myc(MYC) (NM_002467) Human Untagged Clone
Symbol MYC
Synonyms bHLHe39; c-Myc; MRTL; MYCC
Vector pCMV6-XL5
Sequence Data
Fully Sequenced ORF
>OriGene ORF sequence for NM_002467 edited
ATGCCCCTCAACGTTAGCTTCACCAACAGGAACTATGACCTCGACTACGACTCGGTGCAG
CCGTATTTCTACTGCGACGAGGAGGAGAACTTCTACCAGCAGCAGCAGCAGAGCGAGCTG
CAGCCCCCGGCGCCCAGCGAGGATATCTGGAAGAAATTCGAGCTGCTGCCCACCCCGCCC
CTGTCCCCTAGCCGCCGCTCCGGGCTCTGCTCGCCCTCCTACGTTGCGGTCACACCCTTC
TCCCTTCGGGGAGACAACGACGGCGGTGGCGGGAGCTTCTCCACGGCCGACCAGCTGGAG
ATGGTGACCGAGCTGCTGGGAGGAGACATGGTGAACCAGAGTTTCATCTGCGACCCGGAC
GACGAGACCTTCATCAAAAACATCATCATCCAGGACTGTATGTGGAGCGGCTTCTCGGCC
GCCGCCAAGCTCGTCTCAGAGAAGCTGGCCTCCTACCAGGCTGCGCGCAAAGACAGCGGC
AGCCCGAACCCCGCCCGCGGCCACAGCGTCTGCTCCACCTCCAGCTTGTACCTGCAGGAT
CTGAGCGCCGCCGCCTCAGAGTGCATCGACCCCTCGGTGGTCTTCCCCTACCCTCTCAAC
GACAGCAGCTCGCCCAAGTCCTGCGCCTCGCAAGACTCCAGCGCCTTCTCTCCGTCCTCG
GATTCTCTGCTCTCCTCGACGGAGTCCTCCCCGCAGGGCAGCCCCGAGCCCCTGGTGCTC
CATGAGGAGACACCGCCCACCACCAGCAGCGACTCTGAGGAGGAACAAGAAGATGAGGAA
GAAATCGATGTTGTTTCTGTGGAAAAGAGGCAGGCTCCTGGCAAAAGGTCAGAGTCTGGA
TCACCTTCTGCTGGAGGCCACAGCAAACCTCCTCACAGCCCACTGGTCCTCAAGAGGTGC
CACGTCTCCACACATCAGCACAACTACGCAGCGCCTCCCTCCACTCGGAAGGACTATCCT
GCTGCCAAGAGGGTCAAGTTGGACAGTGTCAGAGTCCTGAGACAGATCAGCAACAACCGA
AAATGCACCAGCCCCAGGTCCTCGGACACCGAGGAGAATGTCAAGAGGCGAACACACAAC
GTCTTGGAGCGCCAGAGGAGGAACGAGCTAAAACGGAGCTTTTTTGCCCTGCGTGACCAG
ATCCCGGAGTTGGAAAACAATGAAAAGGCCCCCAAGGTAGTTATCCTTAAAAAAGCCACA
GCATACATCCTGTCCGTCCAAGCAGAGGAGCAAAAGCTCATTTCTGAAGAGGACTTGTTG
CGGAAACGACGAGAACAGTTGAAACACAAACTTGAACAGCTACGGAACTCTTGTGCGTAA
5' Read Nucleotide Sequence
>OriGene 5' read for NM_002467 unedited
TAGATTTCTGTACACGATTCACTATAGGGCGGCCGCGCAATTCGCACGAGGCGGCTAGGG
TGGAAGAGCCGGGCGAGCAGAGCTGCGCTGCGGGCGTCCTGGGAAGGGAGATCCGGAGCG
AATAGGGGGCTTCGCCTCTGGCCCAGCCCTCCCGCTGATCCCCCAGCCAGCGGTCCGCAA
CCCTTGCCGCATCCACGAAACTTTGCCCATAGCAGCGGGCGGGCACTTTGCACTGGAACT
TACAACACCCGAGCAAGGACGCGACTCTCCCGACGCGGGGAGGCTATTCTGCCCATTTGG
GGACACTTCCCCGCCGCTGCCAGGACCCGCTTCTCTGAAAGGCTCTCCTTGCAGCTGCTT
AGACGCTGGATTTTTTTCGGGTAGTGGAAAACCAGCCTCCCGCGACGATGCCCCTCAACG
TTAGCTTCACCAACAGGAACTATGACCTCGACTACGACTCGGTGCAGCCGTATTTCTACT
GCGACGAGGAGGAGAACTTCTACCAGCAGCAGCAGCCAGAGCGAGCTGCAGCCCCCGGCG
CCCAGCGAGGATATCTGGAAGAAATTCGAGCTGCTGCCCACCCCGCCCCTGTCCCCTAGC
CGCCGCTCCGGGCTCTGCTCGCCCTCCTACGTTGCGGTCACACCCTTCTCCCTTCGGGGA
GACAACGACGGCGGTGGCGGGAGCTTCTCCACGGCCGACCAGCTGTAGATGGTGACCGAG
CTGCTGCGAGGAGACATGCTGAACCACAGTTTCATCTGCGACCCGGACGACGAGACCTTC
ATCAAAAACATCATCATCCAGGACTGTATGTGGGAGCGGCTTTTTCGGCGCCGCCAAGCT
CGTCTCAGAGAGCTGGGCCTCTACAGGGCTGAGCGCAAGACAGAGGNAGACCGAACCCGC
CCGCGGGCCCAGNGTCTGCTCCACCTCCACTTGTACTGCAGTATCTGACGCCGCGCTCAC
ATGCAT
3' Read Nucleotide Sequence
>OriGene 3' read for NM_002467 unedited
TACTTTGGACCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTATATTTGC
CAGTTATTTTATTTTTTCTAAAAACAATAGAAAAAATCAACTTTAAAAAGCAAAATGTAC
TTAAATAAAAAAAATTAGGGTTTATAGTACCTATAATACTAGGTACTATATACTAGGATT
GAAATTCTGTGTAACTGCTATAAACGTTTTNATTAAAGTTNTATTTACATTTAATGGCAA
TATTTACAGAGAAACATTGTGTAAATCTTAAAATTTTTTAAAAACAATTCTTAAATACAA
ATCTGTTAAAGAAAAAAAAAAGATGGTAAGCATAAAAAAGTTCTTTTATGCCCAAAGTCC
AATTTGAGGCAGTTTACATTATGGCTAAATCTTTCAGTCTCAAGACTCAGCCAAGGTTGT
GAGGTTGCATTTGATCATGCATTTGAAACAAGTTCATAGGTGATTGCTCANGACATTTCT
GTTAGAAGGAAATCGTTTCCTTACTTTTCCTTACGCACAAAGAGTCCGTAGCTGTTCAAG
TTTGTGTTTCAACTGTTCTCGTCGTTTCCGCAACAAGTCCTCTTCAGAAATGAGCTTTTG
CTCCTCTGCTTGNACGGACAGGATGTATGCTGTGGNCTTTTTAANGGATAACTACCTTNG
GGGGNCCCTTTCATGNTTTCCAACTNCCGGATCTGGTCACGCAGGGCAAAAAAGCTNCGT
TTTAACTCGTTTCTTCTCTGGCGCTNCAAGACGTTGGGTGTTCGCCTCTTGACATTCTCC
TCGGTGTCCGAAGACCTGGGGNCTGTGCATTTTCCGGTGGTGCTGATCTGCTTAAGACTT
TGACACTGTCAACTTGACCCTTTTGCAACAGAAAGTCCTTCGAATGAAGGGAGCCCTGCC
TAATTGCCTAATGTTGGAAACTGGGCACTCTTGAGAACAAGGGCCTTAAGAGGTTTTCTG
GGCCTCACCAAAAGGAACCAACTTTGCCCTTTGCCAAAC
Restriction Sites ECoRI-NOT     
Tag Tag Free
ACCN NM_002467
ORF Size 1365 bp
Insert Size 2100
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reference Data
RefSeq NM_002467.3, NP_002458
RefSeq Size 2377
RefSeq ORF 1365
Locus ID 4609
Cytogenetics 8q24.21
Domains HLH, Myc_N_term, Myc-LZ
Protein Families Stem cell relevant signaling - JAK/STAT signaling pathway, Stem cell relevant signaling - TGFb/BMP signaling pathway, Stem cell relevant signaling - Wnt Signaling pathway, Stem cell - Pluripotency, Embryonic stem cells, Induced pluripotent stem cells, Transcription Factors, Druggable Genome
Protein Pathways MAPK signaling pathway, ErbB signaling pathway, Cell cycle, Wnt signaling pathway, TGF-beta signaling pathway, Jak-STAT signaling pathway, Pathways in cancer, Colorectal cancer, Endometrial cancer, Thyroid cancer, Bladder cancer, Chronic myeloid leukemia, Acute myeloid leukemia, Small cell lung cancer
Gene Summary The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008].
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (4)