PDZD6 (INTU) (NM_015693) Human Tagged Lenti ORF Clone
CAT#: RC218556L2
- LentiORF®
Lenti ORF clone of Human inturned planar cell polarity effector homolog (Drosophila) (INTU), mGFP tagged
"NM_015693" in other vectors (6)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Symbol | PDZD6 |
Synonyms | CPLANE4; INT; OFD17; PDZD6; PDZK6; SRTD20 |
Vector | pLenti-C-mGFP |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC218556).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_015693 |
ORF Size | 2826 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_015693.2 |
RefSeq Size | 3238 bp |
RefSeq ORF | 2829 bp |
Locus ID | 27152 |
UniProt ID | Q9ULD6 |
Cytogenetics | 4q28.1 |
MW | 105.5 kDa |
Gene Summary | Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (PubMed:27158779).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC218556 | INTU (Myc-DDK-tagged)-Human inturned planar cell polarity effector homolog (Drosophila) (INTU) |
USD 862.00 |
|
RC218556L1 | Lenti ORF clone of Human inturned planar cell polarity effector homolog (Drosophila) (INTU), Myc-DDK-tagged |
USD 1,162.00 |
|
RC218556L3 | Lenti ORF clone of Human inturned planar cell polarity effector homolog (Drosophila) (INTU), Myc-DDK-tagged |
USD 1,162.00 |
|
RC218556L4 | Lenti ORF clone of Human inturned planar cell polarity effector homolog (Drosophila) (INTU), mGFP tagged |
USD 1,162.00 |
|
RG218556 | INTU (tGFP-tagged) - Human inturned planar cell polarity effector homolog (Drosophila) (INTU) |
USD 1,062.00 |
|
SC314961 | INTU (untagged)-Human inturned planar cell polarity effector homolog (Drosophila) (INTU) |
USD 950.00 |
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