BCMA (TNFRSF17) (NM_001192) Human Tagged ORF Clone
BCMA/TNFRSF17 (Myc-DDK-tagged)-Human tumor necrosis factor receptor superfamily, member 17 (BCMA/TNFRSF17)
|Product Name||BCMA (TNFRSF17) (NM_001192) Human Tagged ORF Clone|
|Type||Human Tagged ORF Clone|
|Synonyms||BCM; BCMA; CD269; TNFRSF13A|
|E. coli Selection||Kanamycin (25 ug/mL)|
>RC208851 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s)
>RC208851 protein sequence
Red=Cloning site Green=Tags(s)
Sequencher program is needed, download here.
|Restriction Sites||SgfI-MluI Cloning Scheme for this gene Plasmid Map|
|ORF Size||552 bp|
|OTI Disclaimer||The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info|
|OTI Annotation||This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.|
|Product Components||The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.|
|Reconstitution||1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
|RefSeq||NM_001192.1, NM_001192.2, NP_001183.2|
|RefSeq Size||994 bp|
|RefSeq ORF||555 bp|
|Protein Families||Druggable Genome, Transmembrane|
|Protein Pathways||Cytokine-cytokine receptor interaction|
|Gene Summary||The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008]|
|The use of this cDNA Clones has been cited in the following citations:|
An anti-BCMA RNA aptamer for miRNA intracellular delivery
,Catuogno, S;Di Martino, M;Nuzzo, S;Esposito, C;Tassone, P;de Franciscis, V;,
Molecular Therapy - Nucleic Acids 2019
,PubMed ID 31778956
|cDNA Clone Resources|
|SC125656||BCMA/TNFRSF17 (untagged)-Human tumor necrosis factor receptor superfamily, member 17 (BCMA/TNFRSF17)||
|RG208851||BCMA/TNFRSF17 (GFP-tagged) - Human tumor necrosis factor receptor superfamily, member 17 (BCMA/TNFRSF17)||
|RC208851L1||Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 17 (BCMA/TNFRSF17), Myc-DDK-tagged||
|RC208851L2||Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 17 (BCMA/TNFRSF17), mGFP tagged||
|RC208851L3||Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 17 (BCMA/TNFRSF17), Myc-DDK-tagged||
|RC208851L4||Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 17 (BCMA/TNFRSF17), mGFP tagged||