IL10RA (NM_001558) Human Tagged Lenti ORF Clone
CAT#: RC207020L3
- LentiORF®
Lenti ORF clone of Human interleukin 10 receptor, alpha (IL10RA), transcript variant 1, Myc-DDK-tagged
"NM_001558" in other vectors (6)
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | IL10RA |
Synonyms | CD210; CD210a; CDW210A; HIL-10R; IL-10R1; IL10R |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC207020).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_001558 |
ORF Size | 1734 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001558.2 |
RefSeq Size | 3649 bp |
RefSeq ORF | 1737 bp |
Locus ID | 3587 |
UniProt ID | Q13651 |
Cytogenetics | 11q23.3 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway |
MW | 62.9 kDa |
Gene Summary | The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC207020 | IL10RA (Myc-DDK-tagged)-Human interleukin 10 receptor, alpha (IL10RA), transcript variant 1 |
USD 538.00 |
|
RC207020L1 | Lenti ORF clone of Human interleukin 10 receptor, alpha (IL10RA), transcript variant 1, Myc-DDK-tagged |
USD 838.00 |
|
RC207020L2 | Lenti ORF clone of Human interleukin 10 receptor, alpha (IL10RA), transcript variant 1, mGFP tagged |
USD 838.00 |
|
RC207020L4 | Lenti ORF clone of Human interleukin 10 receptor, alpha (IL10RA), transcript variant 1, mGFP tagged |
USD 838.00 |
|
RG207020 | IL10RA (tGFP-tagged) - Human interleukin 10 receptor, alpha (IL10RA), transcript variant 1 |
USD 738.00 |
|
SC108765 | IL10RA (untagged)-Human interleukin 10 receptor, alpha (IL10RA), transcript variant 1 |
USD 539.00 |
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