Nabp2 (NM_027257) Mouse Untagged Clone

SKU MC204052

Nabp2 (untagged) - Mouse oligonucleotide/oligosaccharide-binding fold containing 2B (Obfc2b), (10ug)

Product Data

• Type: Mouse Untagged Clone
• Target Symbol: Nabp2
• Synonyms: 2610036N15Rik; Obfc2b; SSB1
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC026942; CAGCCCCCTGGCTCCCCCTGCGGGTGGCTCGGCGGTGTGCACAGTCCGGCCTGCTGGCTGGCGGGGTGCC ACGGCTCGGGAAGCATGACGACCGAGACCTTCGTGAAGGATATCAAGCCCGGGCTCAAGAATCTGAATCT TATCTTCATTGTACTGGAGACAGGCCGGGTGACCAAGACAAAGGACGGACACGAGGTTCGGACCTGTAAA GTGGCAGACAAAACGGGCAGCATCAACATCTCAGTATGGGACGATGTGGGCAACCTGATCCAACCTGGGG ACATTATCCGACTCACCAAAGGGTATGCTTCAGTGTTCAAAGGTTGTCTGACACTGTACACTGGCCGTGG GGGCGATCTGCAGAAGATTGGAGAATTCTGTATGGTTTATTCCGAAGTCCCTAATTTCAGTGAGCCCAAT CCAGAGTATAACACGCAGCAGGCGCCCAACAAATCGGTGCAGAACAATGACAACAGCCCTACTGCCCCAC AAGCGACCACGGGACCCCCTGCTGCCTCTCCAGCTTCCGAGAACCAGAACGGAAATGGACTGAGCACCCA GCTAGGTCCTGTGGGTGGCCCCCATCCTTCTCACACCCCCTCACATCCCCCCAGCACCCGAATCACTCGA AGTCAACCCAACCACACGCCTTCCGGCCCTCCTGGCCCCTCCAGCAACCCTGTCAGCAACGGCAAAGAAA CCCGAAGAAGCAGCAAGAGATAGCAAGAGATGAGTCTCTCCTTCCTTCCACCACAACCATGATCCAGGCG TCTCTGCCAGAGAACAAGACAGTCTTCTATCAGGCTGCTGGCTTTGGGATTAGAGGATAAAGTAGCTGTG TTTTAGCCACTAAATTTCCCTGGAGGGGTTGGAAGCAGCAGCCTTATCCACCTCAAACTCACGCCCCACC CCACCCCTGTCCTGCTGATGCTGTCTATCCCCTGGGATCCAGGGTCCTCTGCCTGCCCTCCTTTGGAAAA GACAGTGTGGTTTTTGTGTGGGAAATAAGGGTCTAACTGAAATCCCTCCTTCCTAATAAATGTTCCCACT CAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_027257
• Insert Size: 639 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: BC026942, AAH26942
• RefSeq Size: 1106 bp
• RefSeq ORF: 639 bp
• Locus ID: 69917
• UniProt ID: Q8R2Y9
• Cytogenetics: 10 D3
• Summary: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways (By similarity).[UniProtKB/Swiss-Prot Function]