EGFR Mouse Monoclonal Antibody [Clone ID: UMAB95]
Specifications
| Product Data | |
| Clone Name | UMAB95 |
|---|---|
| Application | 10k-ChIP, IF, IHC, WB |
| Recommended Dilution | WB 1:500, IHC 1:100 |
| Reactivity | Human, Monkey, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human EGFR(NP_958440) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide |
| Concentration | 0.5~1.0 mg/ml (Lot Dependent) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 42.4 kDa |
| Gene Name | epidermal growth factor receptor |
| Database Link | |
| Background | The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. provided by RefSeq, Jul 2010 |
| Synonyms | ERBB; ERBB1; ERRP; HER1; mENA; NISBD2; PIG61 |
| Reference Data | |
| Protein Categories | ADC Targets, Cancer: Bladder, Cancer: Brain and CNS, Cancer: Gastrointestinal, Cancer: Gynecologic, Cancer: Head and Neck, Cancer: Lung, CAR-T Targets, Cytokines, Enzyme: Kinases, Growth Factors, Immune system diseases, Membrane Proteins, Secreated Proteins |
| Protein Families | Adult stem cells, Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Secreted Protein, Stem cell relevant signaling - JAK/STAT signaling pathway, Transmembrane |
| Protein Pathways | Adherens junction, Bladder cancer, Calcium signaling pathway, Colorectal cancer, Cytokine-cytokine receptor interaction, Dorso-ventral axis formation, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, GnRH signaling pathway, MAPK signaling pathway, Melanoma, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other "UMAB95" antibodies (2)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| UM500070 | EGFR mouse monoclonal antibody,clone UMAB95 | 100 ul |
$610.00
|
|
| UM500070CF | Carrier-free (BSA/glycerol-free) EGFR mouse monoclonal antibody,clone UMAB95 | 100 ug |
$680.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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