HDAC8 Mouse Monoclonal Antibody [Clone ID: OTI1A4]

SKU TA809651

HDAC8 mouse monoclonal antibody,clone OTI1A4

Product Data

• Clone Name: OTI1A4
• Application: WB
• Recommended Dilution: WB 1:500~2000
• Reactivity: Human, Mouse, Rat
• Antibody Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Human recombinant protein fragment corresponding to amino acids 1-243 of human HDAC8 (NP_060956) produced in E.coli.
• Buffer: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 41.6 kDa
• Gene Name: histone deacetylase 8
• Database Link:
  NP_060956
  Q9BY41
• Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
• Synonyms: CDA07; CDLS5; HD8; HDACL1; MRXS6; RPD3; WTS

Reference Data

• Protein Families: Druggable Genome, Transcription Factors