Cytokeratin 8(KRT8) Mouse Monoclonal Antibody [Clone ID: OTI1B12]

CAT#: TA500021

CK8 (Keratin 8) mouse monoclonal antibody, clone OTI1B12 (formerly 1B12)

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 Product Datasheet for 'TA500021'

USD 350.00


Availability*
In Stock

Size
    • 100 ul

Specifications

Product Data
Clone Name OTI1B12
Applications WB, IHC, IF
Recommend Dilution WB 1:2500~5000, IHC 1:50 - 1:150, IF 1:50 - 1:100
Reactivity Human, Dog, Rat, Monkey
Host Mouse
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 91-381 of human CK8 (NP_002264) produced in E.coli.
Isotype IgG2b
Formulation PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Reconstitution Method Reconstitute with PBS (pH7.3). To use this carrier-free antibody for conjugation experiment, we strongly recommend you to perform another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Concentration 1.00mg/ml
Purification Purified from cell culture supernatant by affinity chromatography
Predicted Protein Size 53.5 kDa
Gene Name keratin 8
Background Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
Synonyms CARD2|CK-8|CK8|CYK8|K2C8|K8|KO
Reference Data
Protein Families Druggable Genome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations