CD1 (CD1D) Mouse Monoclonal Antibody [Clone ID: 51.1]
Specifications
| Product Data | |
| Clone Name | 51.1 |
|---|---|
| Application | FC |
| Recommended Dilution | Flow, IHC, IP |
| Reactivity | Human |
| Antibody Host | Mouse |
| Clonality | Monoclonal |
| Buffer | Aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer |
| Concentration | lot specific |
| Purification | Affinity purified |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | CD1d molecule |
| Database Link | |
| Background | The monoclonal antibody 51.1 reacts with human CD1d, a member of the CD1 family with similarity to the non-polymorphic MHC Class I-like molecules. CD1d is a highly conserved single transmembrane receptor of the Immunoglobulin Superfamily. CD1d can associate with beta-microglobulin another feature showing similarity to MHC class I molecules, but can also exist as a nonglycosylated protein not in association with beta microglobulin. This suggests different control mechanisms for presenting glycolipid containing molecules to CD1d reactive NKT cells. Expression of CD1d is found on B cells of the periphery, in resting monocytes and cortical thymocytes. On intestinal epithelial cells (IEC) expression is polarized. Expression can also be found at low levels intracellularly in hepatocytes. In HCV (hepatitis C virus) livers, CD1d is highly expressed compared to normal controls. |
| Synonyms | CD1A; R3; R3G1 |
| Reference Data | |
| Protein Categories | CD Markers, Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Hematopoietic cell lineage |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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