Decorin (DCN) Human shRNA Plasmid Kit (Locus ID 1634)

SKU TL313548

DCN - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 1634
• Synonyms: CSCD; DSPG2; PG40; PGII; PGS2; SLRR1B
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: DCN - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 1634). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: NM_001920, NM_133503, NM_133504, NM_133505, NM_133506, NM_133507, NM_001920.1, NM_001920.2, NM_001920.3, NM_001920.4, NM_133505.1, NM_133505.3, NM_133503.1, NM_133503.2, NM_133503.3, NM_133507.1, NM_133507.2, NM_133507.3, NM_133506.1, NM_133506.2, NM_133506.3, NM_133504.1, NM_133504.2, NM_133504.3, BC005322, BC005322.1, BM672011, NM_001920.5
• UniProt ID: P07585
• Summary: This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients. [provided by RefSeq, Nov 2015]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient