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Decorin (DCN) Human shRNA Plasmid Kit (Locus ID 1634)

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TL313548
DCN - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
In Control Promo
  $1,013.00
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Specifications
Specifications
Product Data
Locus ID 1634
Synonyms CSCD; DSPG2; PG40; PGII; PGS2; SLRR1B
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components DCN - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 1634). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_001920, NM_133503, NM_133504, NM_133505, NM_133506, NM_133507, NM_001920.1, NM_001920.2, NM_001920.3, NM_001920.4, NM_133505.1, NM_133505.3, NM_133503.1, NM_133503.2, NM_133503.3, NM_133507.1, NM_133507.2, NM_133507.3, NM_133506.1, NM_133506.2, NM_133506.3, NM_133504.1, NM_133504.2, NM_133504.3, BC005322, BC005322.1, BM672011, NM_001920.5
UniProt ID P07585
Summary This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients. provided by RefSeq, Nov 2015
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
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