Frataxin (FXN) Human shRNA Plasmid Kit (Locus ID 2395)

SKU TL312891

FXN - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 2395
• Synonyms: CyaY; FA; FARR; FRDA; X25
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: FXN - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 2395). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: NM_000144, NM_001161706, NM_181425, NM_000144.1, NM_000144.2, NM_000144.3, NM_000144.4, NM_181425.1, NM_181425.2, NM_001161706.1, BC023633, BC023633.2, BC048097, NM_181425.3
• UniProt ID: Q16595
• Summary: This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient