Glutamine Synthetase (GLUL) Human shRNA Plasmid Kit (Locus ID 2752)

SKU TL312740

GLUL - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 2752
• Synonyms: GLNS; GS; PIG43; PIG59
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: GLUL - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 2752). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: NM_001033044, NM_001033056, NM_002065, NM_001033056.1, NM_001033056.2, NM_001033056.3, NM_002065.1, NM_002065.2, NM_002065.3, NM_002065.4, NM_002065.5, NM_002065.6, NM_001033044.1, NM_001033044.2, NM_001033044.3, BC011700, BC011700.2, BC018992, BC018992.1, BC011852, BC011852.2, BC010037, BC031964, BC051726, BC127883, BM662182, BM690132, NM_001033044.4
• UniProt ID: P15104
• Summary: The protein encoded by this gene belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia in an ATP-dependent reaction. This protein plays a role in ammonia and glutamate detoxification, acid-base homeostasis, cell signaling, and cell proliferation. Glutamine is an abundant amino acid, and is important to the biosynthesis of several amino acids, pyrimidines, and purines. Mutations in this gene are associated with congenital glutamine deficiency, and overexpression of this gene was observed in some primary liver cancer samples. There are six pseudogenes of this gene found on chromosomes 2, 5, 9, 11, and 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient