LILRB5 Human shRNA Plasmid Kit (Locus ID 10990)

SKU TL311727

LILRB5 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 10990
• Synonyms: CD85C; LIR-8; LIR8
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: LILRB5 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 10990). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: NM_001081442, NM_001081443, NM_001304457, NM_006840, NM_001081442.1, NM_001081442.2, NM_006840.1, NM_006840.2, NM_006840.3, NM_006840.4, NM_001081443.1, NM_001081443.2, BC025704, BC025704.1, NM_001081442.3
• UniProt ID: O75023
• Summary: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient