Mesothelin (MSLN) Human shRNA Plasmid Kit (Locus ID 10232)

SKU TL311377

MSLN - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 10232
• Synonyms: MPF; SMRP
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: MSLN - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 10232). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: NM_001177355, NM_005823, NM_013404, NM_005823.1, NM_005823.2, NM_005823.3, NM_005823.4, NM_005823.5, NM_013404.1, NM_013404.2, NM_013404.3, NM_013404.4, NM_001177355.1, NM_001177355.2, BC003512, BC003512.1, BC009272, NM_001177355.3, NM_005823.6
• UniProt ID: Q13421
• Summary: This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient