CD30 (TNFRSF8) Human shRNA Plasmid Kit (Locus ID 943)

SKU TL308730

TNFRSF8 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 943
• Synonyms: CD30; D1S166E; Ki-1
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: TNFRSF8 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 943). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: NM_001243, NM_001281430, NM_152942, NM_001243.1, NM_001243.2, NM_001243.3, NM_001243.4, NM_152942.1, NM_152942.2, NM_001281430.1, NM_001281430.2, BC063482, BC073839, BC136400, BC141804, BC171762, NM_001243.5
• UniProt ID: P28908
• Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient