GDAP1L1 Human shRNA Plasmid Kit (Locus ID 78997)

SKU TL307250

GDAP1L1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 78997
• Synonyms: dJ881L22.1; dJ995J12.1.1
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: GDAP1L1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 78997). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: NM_001256737, NM_001256738, NM_001256739, NM_001256740, NM_024034, NR_046353, NM_024034.1, NM_024034.2, NM_024034.3, NM_024034.4, NM_001256738.1, NM_001256740.1, NM_001256739.1, NM_001256737.1, BC000199, BC000199.1, BC009014, NM_001256739.2, NM_024034.6
• UniProt ID: Q96MZ0
• Summary: The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. The protein encoded by this gene is similar in sequence to the human GDAP1 protein. Several transcript variants encoding different isoforms, as well as a noncoding transcript variant, have been found for this gene. [provided by RefSeq, Feb 2012]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient