Drebrin (DBN1) Human shRNA Plasmid Kit (Locus ID 1627)

SKU TL305100

DBN1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 1627
• Synonyms: D0S117E
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: DBN1 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 1627). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: NM_004395, NM_080881, NM_004395.1, NM_004395.2, NM_004395.3, NM_080881.1, NM_080881.2, BC000283, BC007281, BC007567, BC114553, NM_001363541, NM_001364152, NM_001364151
• UniProt ID: Q16643
• Summary: The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient