Dopamine D2 Receptor (DRD2) Human shRNA Plasmid Kit (Locus ID 1813)

SKU TL304907

DRD2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 1813
• Synonyms: D2DR; D2R
• Vector: pGFP-C-shLenti
• E. coli Selection: Chloramphenicol (34 ug/ml)
• Format: Lentiviral plasmids
• Components: DRD2 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 1813). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
• RefSeq: BC021195, NM_000795, NM_016574, NM_000795.1, NM_000795.2, NM_000795.3, NM_016574.1, NM_016574.2, NM_016574.3, NM_000795.4
• UniProt ID: P14416
• Summary: This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient