RAD18 Human shRNA Plasmid Kit (Locus ID 56852)
SKU
TL302132
RAD18 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
In Stock*
Product Data | |
Locus ID | 56852 |
---|---|
Synonyms | RNF73 |
Vector | pGFP-C-shLenti |
E. coli Selection | Chloramphenicol (34 ug/ml) |
Format | Lentiviral plasmids |
Components | RAD18 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 56852). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
RefSeq | NM_020165, NM_020165.1, NM_020165.2, NM_020165.3, BC001302, BC001302.1 |
UniProt ID | Q9NS91 |
Summary | The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens. [provided by RefSeq, Jul 2008] |
shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
Shipping | Ambient |
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