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DR5 (TNFRSF10B) Human shRNA Plasmid Kit (Locus ID 8795)

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TL300915
TNFRSF10B - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
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Specifications
Specifications
Product Data
Locus ID 8795
Synonyms CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Format Lentiviral plasmids
Components TNFRSF10B - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 8795). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_003842, NM_147187, NR_027140, NM_003842.1, NM_003842.2, NM_003842.3, NM_003842.4, NM_147187.1, NM_147187.2, BC001281, BC001281.1, BC043400
UniProt ID O14763
Summary The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. provided by RefSeq, Mar 2009
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
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