Atg7 Mouse shRNA Plasmid (Locus ID 74244)

SKU TG504956

Atg7 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 74244
• Synonyms: 1810013K23Rik; Agp7; Apg7l; Atg7l; Gm21553
• Vector: pGFP-V-RS
• E. coli Selection: Kan
• Format: Retroviral plasmids
• Components: Atg7 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 74244). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
• RefSeq: BC058597, NM_001253717, NM_001253718, NM_028835, NM_028835.1, NM_028835.3, NM_028835.4, NM_001253718.1, NM_001253717.1, NM_001253718.2, NM_028835.5, NM_001253717.2
• UniProt ID: Q9D906
• Summary: This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient