MRP4 (ABCC4) Human shRNA Plasmid Kit (Locus ID 10257)

SKU TG315025

ABCC4 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 10257
• Synonyms: MOAT-B; MOATB; MRP4
• Vector: pGFP-V-RS
• E. coli Selection: Kan
• Format: Retroviral plasmids
• Components: ABCC4 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 10257). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
• RefSeq: NM_001105515, NM_001301829, NM_001301830, NM_005845, NM_005845.1, NM_005845.2, NM_005845.3, NM_005845.4, NM_001105515.1, NM_001105515.2, NM_001301830.1, NM_001301829.1, BC041560, BM687848, NM_001301829.2, NM_001301830.2, NM_001105515.3
• UniProt ID: O15439
• Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient