FMRP (FMR1) Human shRNA Plasmid Kit (Locus ID 2332)

SKU TG312955

FMR1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 2332
• Synonyms: FMRP; FRAXA; POF; POF1; POFX
• Vector: pGFP-V-RS
• E. coli Selection: Kan
• Format: Retroviral plasmids
• Components: FMR1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 2332). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
• RefSeq: NM_001185075, NM_001185076, NM_001185081, NM_001185082, NM_002024, NR_033699, NR_033700, NM_002024.2, NM_002024.3, NM_002024.4, NM_002024.5, NM_001185082.1, NM_001185081.1, NM_001185075.1, NM_001185076.1, BC086957, BC038998, NM_001185082.2, NM_002024.6, NM_001185081.2
• UniProt ID: Q06787
• Summary: The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient