Cytokeratin 8 (KRT8) Human shRNA Plasmid Kit (Locus ID 3856)

SKU TG311828

KRT8 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector, 5µg of each construct provided

Product Data

• Locus ID: 3856
• Synonyms: CARD2; CK-8; CK8; CYK8; K2C8; K8; KO
• Vector: pGFP-V-RS
• E. coli Selection: Kan
• Format: Retroviral plasmids
• Components: KRT8 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector(Gene ID = 3856). 5µg purified plasmid DNA per construct; 29-mer scrambled shRNA cassette in pGFP-V-RS Vector, TR30013, included for free.
• RefSeq: BC008200, NM_001256282, NM_001256293, NM_002273, NR_045962, NM_002273.1, NM_002273.2, NM_002273.3, NM_001256293.1, NM_001256282.1, BC008200.1, BC063513, BC063513.1, BC000654, BC011373, BC073760, BC075839, BM854215, NM_001256282.2, NM_002273.4, NM_001256293.2
• UniProt ID: P05787
• Summary: This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
• shRNA Design: These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
• Shipping: Ambient