TAK1 (MAP3K7) Human shRNA Plasmid Kit (Locus ID 6885)
Specifications
| Product Data | |
| Locus ID | 6885 |
|---|---|
| Synonyms | CSCF; FMD2; MEKK7; TAK1; TGF1a |
| Vector | pRFP-C-RS |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Retroviral plasmids |
| Components | MAP3K7 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector(Gene ID = 6885). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRFP-C-RS Vector, TR30015, included for free. |
| RefSeq | NM_003188, NM_145331, NM_145332, NM_145333, NM_003188.1, NM_003188.2, NM_003188.3, NM_145331.1, NM_145331.2, NM_145332.1, NM_145332.2, NM_145333.2, BC017715, BC017715.2, BM172351, NM_145333.3, NM_145332.3, NM_003188.4, NM_145331.3 |
| UniProt ID | O43318 |
| Summary | The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. provided by RefSeq, Jul 2008 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
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